Longevity Restore
Longevity Restore
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Boost your cellular health and support healthy aging with Longevity Restore from Revive.
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Longevity Restore
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Cellular energy,restored
A complete seven-ingredient formula designed to rebuild NAD+ levels,protect mitochondrial function, and support the repair processes thatdecline with age.
The Formula
100% transparent formula showcasing each ingredient at its researched dose, because not all supplements are created equal. View Supplement Facts.
The Seven Nodes
Production
NMN converts directly to NAD+ via NMNAT enzymes. The 500 mg dose elevated blood NAD+approximately 75 percent over placebo in published trials.
Preservation
CD38 is the enzyme that drives most age-related NAD+ decline. Its expression rises with age and inflammation. Apigenin supports healthy CD38activity, slowing the enzymatic consumption ofthe NAD+ pool.
Activation
Sirtuins, particularly SIRT1, perform much of the cellular repair that NAD+ enables. SIRT1 also benefits from direct activation. Pterostilbene supports SIRT1 activity with approximately 80 percent oral bioavailability versus 30 percent forresveratrol.
Methylation protection
NAD+ biosynthesis and recycling consumemethyl groups. Without replenishment, the SAM cycle gets strained. TMG (trimethylglycine)donates methyl groups directly via the BHMT pathway, supporting both methylation capacity and homocysteine metabolism.
Senescent Cell Support
Senescent cells secrete inflammatory factors that upregulate CD38. Supporting the body's naturalcellular maintenance processes addresses one ofthe upstream drivers of NAD+ decline. Quercefit phytosome quercetin delivers the bioavailability that standard quercetin lacks.
Autophagy
Cellular recycling declines with age. Damaged proteins, defective organelles, and debris accumulate. Spermidine induces autophagy through the elF5A hypusination pathway. A 2024 Nature Cell Biology paper established it as an obligatory mediator of fasting-induced longevity across species.
Tissue Defense
The brain, heart, kidneys, and skeletal muscle mitochondria are most vulnerable to oxidative damage and most reliant on NAD+-dependent repair. L-Ergothioneine has a dedicated cellular transporter (OCTN1) that concentrates itspecifically in these tissues.
Who it is for
From prevention to a complete system.
Adults who tried single-ingredient NMN or NR products and want the complete system.
Adults in their 40s and beyond addressing the NAD+ decline that becomesmeasurable in this decade.
Anyone who wants NAD+ production paired with the six other interventions that determine whether higher NAD+ actually translates into cellular function.
Reported benefits include
Felt in the first weeks, built over months.
FIRST 2–4 WEEKS
Alift indaytime energy and drive
Sharper clarity and processing speed
Better sleep, easier mornings
More vibrant, hydrated skin
3+ MONTHS
Sustained NAD+ for metabolism
Autophagy & clean-up - Spermidine
Improved skinelasticity over time
Cardiovascular & vascular suppor
How These Ingredients Work Together?
This formula is built around the full lifecycle of NAD+, not one hero ingredient. NAD+ is a coenzyme every cell uses for energy metabolism and cellular maintenance, and levels naturally decline with age. The seven ingredients work across four stages of that lifecycle: making it, preserving it, putting it to use, and clearing the cellular debris that speeds its loss.
Formulated with Dr. Adeel Khan, MD
Aglobally recognized pioneer in regenerative medicine applying clinical research to build what the supplement industry hasn't.
Customer reviews
Frequent Questions
What's in this formula, and what does it do?
What's in this formula, and what does it do?
Combines NMN (500mg) for NAD+ production, Spermidine (10mg) for cellular recycling (autophagy), Pterostilbene, TMG (500mg) to replenish methyl groups, Quercefit, and L-Ergothioneine for cellular health.
What's the difference between this and Revive MD's Longevity Core?
What's the difference between this and Revive MD's Longevity Core?
Longevity Restore centers on NMN as a direct NAD+ precursor, plus spermidine for autophagy support. Longevity Core focuses on mitochondrial health through Urolithin A, PQQ, and CoQ10, plus Apigenin for NAD+ preservation. Some use both.
How do I take it, and when's the best time?
How do I take it, and when's the best time?
Take with a meal for optimal absorption of the fat-soluble and polyphenolic ingredients.
How long until I notice a difference?
How long until I notice a difference?
Most NAD+ trials show measurable blood NAD+ elevation within 2 weeks and functional
improvements within 4 to 12 weeks of consistent daily use.
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